Joints Centre

Research & Trials

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Research

A Study of the Effect on Pain Control of Treatment With Fentanyl, Administered Through the Skin, in Patients With Rheumatoid Arthritis or Osteoarthritis

8 Nov 2007
The purpose of this study is to assess the degree of pain control achieved by treatment with fentanyl, administered via adhesive patches applied to the skin ('transdermal system') in patients with ... › More

A Clinical Study in the Use of Orthotics in Treating Pain in the Front of the Knee

28 Jul 2007
This project will conduct a randomised clinical trial to evaluate the relative benefits of orthotics as the sole treatment of patellofemoral pain syndrome and also when combined with physiotherapy. ... › More

Abatacept in the Treatment and Prevention of Active Systemic Lupus Erythematosus (SLE) Flares in Combination With Prednisone

14 May 2007
The purpose of this clinical research study is to learn whether Abatacept can treat and prevent lupus flares; specifically, active lupus flares in at least one of three organ systems: skin (discoid ... › More

Objectives Study in Rheumatoid Arthritis (The OSRA Study)

16 Apr 2007
Rheumatoid synovitis causes largely irreversible damage to cartilage, bone and ligaments. Drug therapy aims to provide symptomatic relief but more importantly to suppress synovitis, or 'disease ... › More

Tai Chi or Hydrotherapy for People With Osteoarthritis of the Hip(s) or Knee(s)

9 Mar 2007
The aim of this study is to determine, in the framework of a randomized controlled clinical trial, whether Tai Chi can affect measurable improvements in self-reported outcomes such as pain, physical ... › More

Trial of Physiotherapy and Corticosteroid Injections in Lateral Epicondylalgia

18 Feb 2007
This randomised controlled trial will evaluate the role of manual therapy and therapeutic exercise and corticosteroid injections in the treatment of lateral epicondylalgia (tennis elbow). › More

Pain and Stress Management for People with Rheumatoid Arthritis

4 Feb 2005
Self-management of rheumatoid arthritis (RA) symptoms using written emotional disclosure (ED), coping skills training (CST), or a combination of both may benefit people with RA. The purpose of this ... › More

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of the Safety, Efficacy, and Pharmacokinetics of the Human Anti-TNF Monoclonal Antibody Adalimumab in Children With Polyarticular Juvenile Rheumatoid Arthritis

4 Feb 2005
This is a multicenter, Phase III randomized, placebo-controlled study in which polyarticular JRA subjects who are either MTX treated or non-MTX treated will initially receive Adalimumab by ... › More

Trials

A Study of the Safety and Efficacy of Intravenous CNTO 148 (Golimumab) in Patients With Active Rheumatoid Arthritis Despite Methotrexate Therapy

9 Jun 2007
The primary purpose of this study is to assess the clinical effectiveness and safety of intravenous (IV- injection directly into the vein) golimumab infusions every 12 weeks in patients with active ... › More

Study Evaluating Etanercept and Sulphasalazine in Ankylosing Spondylitis

4 May 2007
The purpose of this study is to compare the efficacy of etanercept and sulphasalazine in the treatment of Ankylosing Spondylitis. › More

Study Evaluating Etanercept on Skin and Joint Disease in Psoriatic Arthritis

6 Apr 2007
To assess the efficacy of two different treatment regimens of etanercept in psoriasis subjects with psoriatic arthritis with respect to both the skin and joint manifestations. › More

Safety and Efficacy Study of Etanercept (Enbrel¶©) In Children with Systemic Onset Juvenile Rheumatoid Arthritis

23 Dec 2004
This study will determine the efficacy of etanercept in children with systemically active systemic onset juvenile rheumatoid arthritis (SOJRA). › More

The support of the following commercial entities are greatfully acknowledged: